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From birth Same strain and dose as in the colic trials

Semper Dråber

Drops with 1 strain, L. reuteri DSM 17938, for full-term babies from birth

Shop: Med24

In short: Drops with 1 strain, L. reuteri DSM 17938, 100 million CFU in 5 drops. That is the strain and dose used in the trials in babies with colic. The drops contain no vitamin D, so the baby still needs ordinary vitamin D drops.

Price

DKK 165.95/ 10 ml (about 50 days' supply)RRP: DKK 219.95

-24%

Price at Med24, checked 2026-10-24. May have changed since.

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Research

What the research shows

The studies most often mentioned in connection with Semper Dråber, and what they actually studied. Notice whether the study tested this exact product.

Evidence: High PMID: 29279326

Lactobacillus reuteri to Treat Infant Colic: A Meta-analysis

Sung V, D'Amico F, Cabana MD, et al. · Pediatrics (2018)

Key finding: Pooled analysis of 4 double-blind trials with 345 babies with colic: with L. reuteri DSM 17938 the babies cried and fussed on average 25 minutes less a day after 21 days than with placebo. The difference was clear in breastfed babies and not significant in formula-fed ones.

Evidence: Moderate PMID: 24639271

Diarrhea in preschool children and Lactobacillus reuteri: a randomized controlled trial

Gutierrez-Castrellon P, Lopez-Velazquez G, Diaz-Garcia L, et al. · Pediatrics (2014)

Key finding: Trial with 336 children aged 6 to 36 months in Mexican day care centres, 100 million CFU daily for 3 months: fewer and shorter episodes of diarrhoea and respiratory infection than with placebo, also 3 months after the children had stopped.

Evidence: Moderate PMID: 42811720

Limosilactobacillus reuteri DSM 17938 in pediatric functional abdominal pain disorders and functional constipation: A systematic review and meta-analysis of randomized controlled trials

Quatrale G, Bianchi M, Colecchia L, et al. · Journal of Pediatric Gastroenterology and Nutrition (2026)

Key finding: Pooled analysis of 5 trials in children with functional abdominal pain and 5 with constipation: no clear difference from placebo in abdominal pain or in how often the children had a bowel movement.

Contents

Bacterial strains in Semper Dråber

The strains as the manufacturer declares them. There are no approved health claims for probiotic strains in the EU, so we only say something about a strain where there is a source.

Lactobacillus100 million CFU per daily dose

Limosilactobacillus reuteri DSM 17938

The strain is also called Protectis. It has mainly been studied in babies with colic, and the trials used the same dose.

Protocol & Use

How to use Semper Dråber

Dosage as the manufacturer instructs for Semper Dråber.

Product type
Drops in oil
Daily dose
5 drops a day (100 million CFU)
Best time
Once a day. The manufacturer gives no time of day.
Preparation
Shake the bottle for at least 10 seconds before use

Step-by-step guide to Semper Dråber:

  1. Shake the bottle for at least 10 seconds.
  2. Give 5 drops once a day.
  3. Do not mix the drops into food or drink warmer than 37 °C.
  4. Store the bottle at room temperature, no more than 25 °C.

Important for Semper Dråber: The manufacturer recommends the drops only for full-term babies from birth. If your baby was born prematurely, ask the doctor or the neonatal unit.

Who is Semper Dråber for?

  • Full-term babies from birth, older children and adults (manufacturer's information)
  • Parents who want to give the strain from the colic trials and give vitamin D drops separately

Good to know & precautions:

  • Contains no vitamin D. The Danish Health Authority recommends 10 µg of vitamin D a day from 2 weeks to 4 years
  • If your baby has colic, talk to the health visitor or doctor before trying anything
  • Not for premature babies unless agreed with the doctor
  • Do not exceed the recommended daily dose

Semper Dråber

DKK 165.95RRP: DKK 219.95 -24%· Sold by Med24

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